Power approximation of the transmission disequilibrium test
Articles
Šarūnas Germanas
Vilniaus universitetas
Audronė Jakaitienė
Vilniaus universitetas
Published 2012-12-25
https://doi.org/10.15388/LMR.B.2012.11
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Keywords

transmission disequilibrium test
power
Poisson distribution

How to Cite

Germanas Šarūnas and Jakaitienė A. (2012) “Power approximation of the transmission disequilibrium test”, Lietuvos matematikos rinkinys, 53(B), pp. 56–61. doi: 10.15388/LMR.B.2012.11.

Abstract

In this paper we apply Poisson distribution in order to approximate the power of the Transmission Disequilibrium Test (TDT). In this research we calculated the power of the TDT for different values of sample size n and different values of allele transmission frequencies p. The research showed that Poisson approximation have smaller errors than Normal approximation when the power is between 0.8 and 0.95 and sample size m is equal or bigger than 50.

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