Pump operations in locally advanced thoracic malignancies
Oncology
Saulius Cicėnas
Vytautas Jonas Sirvydis
Giedrius Uždavinys
Gintaras Kalinauskas
Renatas Aškinis
Sigitas Zaremba
Published 2013-01-31
https://doi.org/10.6001/actamedica.v19i4.2551
PDF

Keywords

pump operations
surgical treatment
thoracic malignancies

How to Cite

Cicėnas S., Sirvydis V. J., Uždavinys G., Kalinauskas G., Aškinis R. and Zaremba S. (2013) “Pump operations in locally advanced thoracic malignancies”, Acta medica Lituanica, 19(4), pp. 417-420. doi: 10.6001/actamedica.v19i4.2551.

Abstract

Background. The study objective is to evaluate the efficacy of pump operations in locally advanced IIIB (T4N0-1M0) lung cancer and other thoracic malignancies and the results of treatment. Materials and methods. In the period 2003–2011, 6 patients (pts) with locally advanced thoracic malignancies underwent surgery in the Center of Cardiac Surgery of Vilnius University Hospital Santariskiu Clinics (VUH SC). Patients’ characteristics and stage: lung cancer – 3 pts (50.0%), stage IIIB (T4N0-1M0), sarcoma of mediastinum – 2 pts (33.3%), fibrous tumour of mediastinum – 1 pt (16.7%). Patients according to morphology: squamous cell carcinoma – 3 pts (50.0%), neuroangiosarcoma – 1 pt (16.7%), neurosarcoma – 1 pt (16.7%), solitary fibrous tumour – 1 pt (16.7%). After surgery patients received adjuvant treatment: 3 pts with lung cancer received 4 cycles of chemotherapy Gemcitabine with cisplatinum, 2  pts with angiosarcoma received radiation therapy 66 Gy and 6 cycles of chemotherapy Ifosfamide. Results. We performed pneumonectomy with left atrium resection  –  2  pts (33.3%), left pneumonectomy with aorta resection  –  1  pt (16.7%), left atrium resection with left upper lobectomy  –  1  pt (16.7%), mediastinum resection with chest wall reconstruction – 1 pt (16.7%), left pneumonectomy – 1 pt (16.7%). We had no complications after pump operations. Median survival of patients with lung cancer was 2.5 ± 0.5 years, with angiosarcoma 3.5 ± 1.0 years. Five-year survival was 25%. Conclusions. 1. Pump operations are safe and possible in locally advanced thoracic malignancies. 2.  Pump operations and adjuvant treatment may prolong median survival in IIIB (T4N0-1M0) lung cancer patients by 2.5 ± 0.5 years and in angiosarcoma patients by 3.5 ± 1.0 years.
PDF
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Most read articles by the same author(s)

1 2 3 4 > >>