Computer Simulation of Amperometric Biosensor Response to Mixtures of Compounds
R. Baronas
Vilnius University, Lithuania
J. Christensen
The Royal Veterinary and Agricultural University, Denmark
F. Ivanauskas
Vilnius University; Institute of Mathematics and Informatics, Lithuania
J. Kulys
Institute of Biochemistry, Lithuania
Published 2002-12-05



How to Cite

Baronas R., Christensen J., Ivanauskas F. and Kulys J. (2002) “Computer Simulation of Amperometric Biosensor Response to Mixtures of Compounds”, Nonlinear Analysis: Modelling and Control, 7(2), pp. 3-14. doi: 10.15388/NA.2002.7.2.15190.


A mathematical model of amperometric biosensors has been developed. The model bases on non-stationary diffusion equations containing a non-linear term related to Michaelis-Menten kinetic of the enzymatic reaction. The model describes the biosensor response to mixtures of multiple compounds in two regimes of analysis: batch and flow injection. Using computer simulation, large amount of biosensor response data were synthesised for calibration of a biosensor array to be used for characterization of wastewater. The computer simulation was carried out using the finite difference technique.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Please read the Copyright Notice in Journal Policy

Most read articles by the same author(s)

1 2 > >>