Computer Simulation of Amperometric Biosensor Response to Mixtures of Compounds
Articles
R. Baronas
Vilnius University, Lithuania
J. Christensen
The Royal Veterinary and Agricultural University, Denmark
F. Ivanauskas
Vilnius University; Institute of Mathematics and Informatics, Lithuania
J. Kulys
Institute of Biochemistry, Lithuania
Published 2002-12-05
https://doi.org/10.15388/NA.2002.7.2.15190
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Keywords

reaction-diffusion
modelling
biosensor

How to Cite

Baronas R., Christensen J., Ivanauskas F. and Kulys J. (2002) “Computer Simulation of Amperometric Biosensor Response to Mixtures of Compounds”, Nonlinear Analysis: Modelling and Control, 7(2), pp. 3-14. doi: 10.15388/NA.2002.7.2.15190.

Abstract

A mathematical model of amperometric biosensors has been developed. The model bases on non-stationary diffusion equations containing a non-linear term related to Michaelis-Menten kinetic of the enzymatic reaction. The model describes the biosensor response to mixtures of multiple compounds in two regimes of analysis: batch and flow injection. Using computer simulation, large amount of biosensor response data were synthesised for calibration of a biosensor array to be used for characterization of wastewater. The computer simulation was carried out using the finite difference technique.

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